Synthesis and Characterization of poly (P-Paracetamol Styrene Sulfonate )and Study of its Controlled Release


In this paper the poly (p-paracetamol styrene sulfunate ),P2 was prepared from reaction of poly (p-styrene sulfunylchloride )P1 with paracetamol.Poly (p- styrene sulfonyl chloride)P1 was prepared fromsulfunation of polystyrene with chlorosulfonic acid at 0 oC.All the physical properties of polymer P2 was studied and itwas characterized by IR spectroscopy and the releasecharacteristics of a new polymer P2 were studied in alkalineand acidic media .The hydrolysis data showed that release rates are stronglydependent on the PH of the medium , and the temperature.