EFFECT OF DICHLORVOS PESTICIDE ON FERTILITY OF LABORATORY MALE MICE (Mus musculus L.)

Abstract

Dichlorvos is one of organophosphate insect pesticides which is widely distributed in environment. This study deals with the effect of this pesticide on sperms number , sperm abnormalities and spermatogenesis in laboratory male mice (Mus musculus L.) which were treated with (0.1 mg/day , 0.05 mg/day ) of the pesticide for a period of 15 day. intraperitoneal injection of Dichlorvos in laboratory mice resulted in a significant decrease in sperms number with both doses as compared with the control group. The result also showed a significant increase of sperm abnormalities with both doses. Moreover, pesticide injection caused a significant decrease in spermatogonia and primary spermatocyte with both doses whereas the statistical analysis did not show any significant difference in tubular diameter when compared with the control group.