Synthesis of Phenolphthalein-formaldehyde resin and study of it's antibacterial activity

Abstract

The Reaction of phenolphthalein with formaldehyde in the presence of Sodium hydroxide afforded phenolphthalein-formaldehyde (PPF), and the structure was confirmed by FT-IR spectrum study. The in vitro antibacterial activity of the synthesized polymer was investigated and showed remarkable inhibition against both Escherichia Coli (Gram -) and Staphylococcus aureus (Gram +). The MIC (Minimal Inhibitory Concentration) values were determined based on Disc Diffusion Method. Allowing the possibility of using the polymer as water sterilizer.