Diagnosis of Chronic Disseminated Intravascular Coagulation in 72 Cancer Patients According to the International Society on Thrombosis and Hemostasis Score System

Abstract

Background: Chronic disseminated intravascular coagulation (DIC) is a well- recognized life- threatening haemostatic complication that occurs frequently in patients suffering from Cancer.Aim of the study: Evaluation of the diagnosis of chronic DIC, according to the International Society on Thrombosis and Hemostasis (ISTH) score system.Methods: From July, 2006 to April, 2007, 72 pre-operative and pre-treatment patients with hematological and solid tumor malignancies, presenting to the Hewa Hospital for Oncology in Sulaimani, and 16 healthy volunteers served as controls were included in this study for the diagnosis of chronic DIC according to the ISTH score system.Results: Among screened patients, a total of 30 (42%) were diagnosed with chronic DIC, which were solid tumors and hematological malignancies.Conclusions: There is a high frequency of chronic DIC among pretreatment and preoperative cancer patients. This study is the first that used ISTH score system for the diagnosis of chronic DIC in cancer patients. Keywords: Chronic DIC, ISTH diagnostic score system, cancer.