Estimation of serum calcium and parathyroid hormone (PTH) levels in diabetic patients in correlation with age and duration of disease

Abstract

Background: A potentially important role for calcium in the development of diabetes has been implicated. This study aims to the assess serum calcium (Ca) and parathyroid hormone (PTH) levels in diabetic patients and the correlation between calcium and PTH with the duration of the disease and age of the patients.Material & Method: This study included 30 patients who had type 2 diabetes who attended outpatients’ clinic of Baghdad Teaching Hospital from June 2009 to July 2009. Those patients were varying in their ages (30-70 years) and duration of disease (1-22 years) compared with 20 apparently healthy controls (non diabetic), with the same range of age. Ca estimation was done by atomic absorption method, while PTH level was estimated by ELISA kit.Results: In this study there was a significant decrease in serum PTH and a significant increase in serum calcium (p<0.0001) of the patients compared with the controls. Also there was a strong direct correlation between patients’ Ca & PTH levels (r=0.3), while a strong inverse correlation was found between patients’ age and their calcium level (r= -0.46)Conclusion: There was a decrease in parathyroid hormone level, and increased calcium level in serum diabetic patients.Key words: Diabetes, Calcium, PTH.

Keywords

Diabetes, Calcium, PTH