Effect of methanolic extracts of different parts of Liquorice Glycyrrhiza glabra L. on growth of some pathogenic bacteria and fungus Candida albicans

Abstract

Methanolic extracts of different parts of Glycyrrhiza glabra L. (roots with rhizomes, stems, leaves and seeds), were tested for antibacterial and antifungal activities. Antibacterial study performed against six bacteria (Staphylococcus aureus, Bacillus cereus, Escherishia coli, Pseudomonas aeruginosa, Salmonella typhi and Shigella dysenteriae), and antifungal activity performed against one fungus (Candida albicans). The effect of the extracts was tested separately using Agar- well diffusion method. Indicated that investigated plant parts have potent activity against all microorganisms especially at 2.5 and 2.0 µg/ml. the inhibition zone in seeds extract reached 37& 35 mm for bacteria S. aureus and B. cereus respectively, by compared with Streptomycin and also reached in seeds extract 20 mm for fungus by compared with Nystatin. Also the results showed that seeds extract have a good effect as antibacterial while the roots extract showed a best effects from other extracts as antifungus.