Association of HLA – I and HLA – II molecules with Mycobacterium Tuberculosis Infection.

Abstract

Aim: To study the association of HLA-I and HLA-II molecules in lymphocytes suspension obtained from tuberculosis patients .Material and Methods : Patients : 105 positively diagnosed patients as having tuberculosis and 40 healthy control subjects. Blood from all subjects tested were exposed to micro assay and a panel of monoclonal antibodies (McAbs) to HLA-I and HLA-II antigens .Results : Lymphocytes suspension showed that there is an association between HLA-A30(19), DQ6, DR1, B18, whereas negative association recorded when HLA-B13, DR8, DQ4, is seen .