Salivary uric acid, total protein and periodontal health status variation in relation to the body mass index (A Clinical and Biochemical study)

Abstract

Background: Obesity is the fastest growing health-related problem in the world. It plays an affecting role in thebiochemistry of many serious systemic diseases like diabetes and CVD. Periodontitis appeared to have a reciprocalrelationship with both, obesity on one hand side and the serious systemic diseases on other hand.Aim of study: is to investigate the effect of obesity and periodontitis on the salivary flow and its uric acid and total protein.Material and method: Eighty one male, aged 30-40 y, systemically healthy, no smokers, having chronic periodontopathicinflammation(gingivitis and / or periodontitis), grouped in three according to BMI, each of 27; GI; normal weight, G2; preobese,and G3; obese. PL.I, GI, BOP, PPD, CAL were clinically recorded at the same hour of unstimulated salivacollection. Probing depth and attachment levels were arranged in scales.Result: Obese group showed significantly high scores of all periodontal data over other 2 groups. Pre-obese showed alsosignificant high scores on the normal weighted. Uric acid was insignificantly low in obese than other 2 groups, while thetotal protein, in obese was significantly higher than other 2 groups, as the salivary flow did. The differences in uric acidand total proteins values were insignificant between normal weights and pre-obese. A significant positive correlationhave been found among periodontal parameters, scale 1 PPD/CAL salivary flow, uric acid, total protein and obesity.Conclusion: Obesity is not only enhancing the severity of periodontopathy, but also modifies the chemical Constituents ofsaliva.