Biochemical analysis and periodontal health status in type 1 and type 2 diabetes (Comparative study)


Background: Diabetes mellitus is a group of metabolic disorders with one common manifestation: hyperglycemia.This study aimed to evaluate the periodontal health status and cera reactive protein (C.R.P) in saliva in type1 andtype 2 diabetic patients and compared with healthy subjects.Material and method: Total samples composed of eighty participants, the samples were divided to study group (60diabetic patients) which include type 1 and type 2 diabetic patients and control group (20 healthy subjects).Theywere non-smokers male patients of age range 25-55 years old. Periodontal health status was estimated by measuringplaque index (PL.I), Gingival index (G.I), Bleeding on probing (BOP), Probing pocket depth (PPD) and Clinicalattachment level CAL).Five mls of un stimulated whole saliva was collected for estimation of C.R.P.Result: The result showed that the mean C.R.P in saliva was higher in study group compared to control group.Nosignificant difference in PL.I and significant difference in G.I, BOP, PPD and CAL between type 1 and type 2 ofdiabetes .There was weak correlation between clinical periodontal parameters and biochemical parameters.Conclusion: salivary C.R.P may be involved in the interaction of periodontitis in type 1 and type 2 diabetic patients