Abstract

4-amino sulphamethaoxazole was reacted with chloro acetyl chloride to convert the amino group to 4-chloro acetyl amino sulphamethaoxazole (compound 1).The amide was then allowed to react with potassium thiocyanate to prepare 4-(2-imino-4-oxo-thiazolidinyl) compound(2) which contained thiazolidinone ring. Some aromatic amines were reacted with 4-chloro acetyl amino sulphamethaoxazole compound (1) to prepare 4-substituted anilino acetyl amino sulphamethaoxazole compounds (1A-H). 4-(2-imino-4-oxo-thiazolidinyl) Compound (2) was reacted with different aromatic aldehydes to prepare 4-(5-arylidene-2-imino-4-oxo-thiazolidinyl sulphamethaoxazole) compounds (2A-H). The prepared compounds were identified and for the prepared compounds such as (1D,1H,2,2B,2E) 1H-n.m.r. spectra was used.

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The article was added to IASJ on 2013-05-19

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