Effect of LPS Extracted from Campylobacter coli on Lymphocyte Transformation

Abstract

Lipopolysaccharide (LPS) of Campylobacter coli was extracted by using digestive enzyme and hot phenol method. The effect of LPS on lymphocyte transform was studies by lymphocyte transformation index for twenty blood samples were collected from apparently healthy control.The results were showed significant differences (P< 0.05) between samples which treatrd with phytohemagglutnin PHA (66.1 ± 0.6) and the samples which treated with LPS of C. coli (74.2 ± 0.8) when compared with control, this lead to suggest that the LPS extracted from C. coli may play a role as a mitogen to transformed lymphocytes.