Assessment of Body Mass Index & Nutritional Status in Pulmonary Tuberculosis Patients

Abstract

AbstractBackground: Pulmonary tuberculosis (PTB) is a chronic infectious disease which affects nutritional status of the patients. The presence of poor nutritional status in pulmonary tuberculosis patients has been one of the most important determining factors in recommending adjuvant nutrient therapy to prevent oxidative stress and further complication. The aim of the study: This study was designed to assess the nutritional status and body mass index (BMI) of pulmonary tuberculosis patients. Patients and methods: During the period 1st of June 2010 to 30th of May 2011, a case-control study was done on 60 patients with active pulmonary tuberculosis who attending chest and respiratory disease institute in Baghdad, and 60 controls, Levels of total serum protein (TP), S. albumin (ALB.), S. globulin, S. triglyceride (TG), total serum cholesterol (TC), high density lipoprotein cholesterol (HDLC), low density lipoprotein cholesterol (LDLC), and body mass index (BMI) were measured for both groups.Results: The mean levels of TP (59.5 ± 0.8g/dl), ALB (23.4 ± 1.8g/dl), TC (138.7 ± 4.9mg/dl), HDLC (32.2 ± 4.0mg/dl), LDLC (86.5 ± 1.3mg/dl) and TG (62.4 ± 1.3mg/dl) were significantly lower while the level of globulin (36.2 ± 1.2g/dl) was significantly higher in pulmonary tuberculosis patients when compared with controls (TP=81.2 ± 4.5g/dl; ALB= 50.0 ± 4.0g/dl; TC = 213.5 ± 26.8mg/dl; HDLC = 57.4 ± 8.5mg/dl; LDLC = 161.1 ± 28.3mg/dl; TG= 148.5± 37.1mg/dl; globulin = 31.4 ± 1.7g/dl respectively). (P <0.05), The body mass index (16.9 ± 1.1kg/m2) was significantly lower when compared with controls (BMI= 23.5 ± 2.1kg/m2). (P <0.05)Conclusion: There is a significant degree of nutritional depletion and weight loss in PTB patients than in general population, BMI is considered to be a useful technique for assessment of nutritional state of pulmonary tuberculosis patients, The nutritional derangement could call for prompt nutritional intervention in the management of pulmonary tuberculosis patients.Key Words: Assessment Pulmonary Tuberculosis, Body Mass Index, Nutritional State.