Clinico-Histopathological Study of Calcinosis Cutis among Iraqi Patients


Abstract:Background: Cutaneous calcification results from deposition of insoluble calcium phosphorous salts in the cutaneous tissues. There are wide clinical presentations of calcinosis cutis and it's a rare dermatological problem. However serious implication may arise due to delayed diagnosis.Objective: To highlight and elaborate different clinical types of calcinosis cutis among Iraqi patients. Patients and Methods: This observational, descriptive, clinical and histopathological study was done in Department of Dermatology- Baghdad Hospital-Medical City, Baghdad, Iraq during the period from January 1997-Decmber 2012.History, examination and complete investigations if needed were done for each patient including all demographic points related to the disease. Excisional or incisional biopsies from each patient for histopathological evaluation were done. Results: A total of 72 patients were included. They were 46 (63.01%) females and 27(38%) males. Their ages ranged from 3.5– 65(24.74±15.9) years. They were classified into 2 groups: Group A the dystrophic type with 65(89.04%) patients and was subdivided into calcinosis cutis universalis which constituted from 6(8.2%) cases. The 2nd subtype is calcinosis cutis circumscriptum which consist of 58(79.7%) cases. Group B: 8 (11.11%) patients with idiopathic type, 1 (12.5%) with idiopathic scrotal calcinosis and 2(25%) with subepidermal calcified nodule. Conclusion: Calcinosis cutis is a rare medical problem with multiple etiological factors in which we see calcified deposits mainly in the skin. This is the first report appeared from Iraq.Keywords: Calcinosis cutis, pilometricoma, pseudoxanthoma elasticum, Iraqi patients.