Effect of natural bee honey in the healing of cutaneous wounds infected Pseudomonas aeruginosa with in white rats

Abstract

The present study was conducted at the Department of Biology in the College of Education for Girls - University of Kufa / Najaf for the period from November 2010 until December 2011 and aims to study the effec of natural bee honey dressing in skin wound flammation in the wounded white rats , infected with Pseudomonas aeruginosta and compared with the gentamycin dressing In vivo. The results of microscopic examination of wounded skin tissue in the white rat groups infected with P. aeruginosa and treatment with natural honey dressing showed severe infiltration of the cells neutrophil cells, especially on the first day of a wound compared to other groups of control and gentamycin, and notes that the number of neutrophil cells, has decreased in the coming days of treatment and completely disappeared in the 14th day of treatment with natural honey dressing. Also observed an increase in the number of macrophages on the 7th day of treatment with natural honey dressing .When counting macrophages observed the existence of significant differences between groups of control and gentamycin and the groups of rats treated with natural honey dressing on the 7th day and the macrophages population is large and significant in the groups treated with natural honey dressing , especially on the 14th day. Also seemed formation of blood and lymphatic vessels on the 7th day, while the composition was heavily in 21st of treatment with natural honey dressing. and highly significant than control and gentamycin groups .The results showed that the growth of collagen fibers appeared on the 7th day and was more pronounced and significantly and moral on the 14th and 21st day of treatment with natural honey dressing, compared with the gentamycin and control groups.