A comparative Study of Liver Regeneration After Partial Hepatectomy in Young and Adult Goat (Caprus Hircus)


The study was carried out to compare the regenerated ability of liver between young and adult goats after partial hepatectomy and evaluate the regeneration of these two different periods depend on histological study. Twelve healthy female goats were used. The animals were divided according to the age, six adult goat aged between 2 - 3 years, and six young goat aged between 2 - 3.5 months. Each group was subdivided into equal subgroups according to the time of laparoscopic biopsy postoperative at 21days and 60 day. All the operations were performed under general anesthesia by Xylazine hydrochloride 0.1mg/kg B.W., Ketamine hydrochloride 4 mg/kg B. W. intramuscularly. The ventral abdominal was prepared for aseptic surgical technique. The animals were fixed at dorsal recumbencey position. And under general anesthesia. Skin incision of about 13-15cm was created at parallel to the paracostal coast from the right side. Then liver was exposed and peripheral edge of its was holded by hand of assistant surgeon. About 5cm width and 4 cm depth was surrounded by horizontal interrupted. This area was cut using scissors. The histological outcome of these two groups indicated that the young goat has regenerated ability higher than adult goat of animals