Effect of Olive Oil Extract on some Biochemical Parameters in Alloxan Induced Diabetic Mice


Olive oil extract was studied for diabetes mellitus that induced by alloxan in mice to development herbal medicine against the non communicable disease. We have measured the fasting blood glucose level (serum). Hyperglycemia and hyperlipidemia are two important characters of diabetes mellitus. Hyperlipidemia developed in these experimental diabetic mice was assessed by quantification of total cholesterol (TC), high-density lipoprotein cholesterol (HDLc), and triglyceride (TG) in serum, so the extract of olive oil have some remedial effects against alloxan-induced diabetic mice. Forty five adult male mice used in this study, animals were divided into three equal groups :Control without any treatment (A), alloxan treated (B) and group(C) induced diabetic and treated with the extract of olive oil (0.5ml/100g B.W). All animals were sacrificed 2,4,6 weeks post treatment respectively. After treatment of extract of olive oil in alloxan-induced diabetic mice the result showed a significant remedial effect on blood glucose level, None of the extract has any metabolic toxicity induction in general (by measuring level of GPT, GOT and ALP).