Histomorphometric analysis of bone deposition at Ti implant surface dip-coated with hydroxyapatite (In vivo study)


Background: Synthetic hydroxyapatite,(Ca10(PO4)6(OH2) can directly bond to bones without infection and fibrousencapsulation, thus is regarded as bioactive and biocompatible. The aim of the study was the estimation ofmicroarchitecture bone parameters include bone mass (gm/cm2) cortical bone width (mm), thread width (mm),marrow space star volume analysis (V*m) and osteoblast, osteocyte cell number.Materials and methods: Ninety-six (96) commercially pure titanium CpTi) used in this study, (48) implants were coatedwith HA by dipping coating and (48) implants were used as control. They were inserted in (32) Newzland white rabbitsand followed for 2 & 6 weeks. Mechanical torque removal test and histomorphometric analysis of bonemicroarchiteture were performed for evaluation of osseointegration.Results: Results revealed, Torque values were increased with advancing time for coated and uncoated groups. Andspecifically dip coated implant showed high value in comparison to control. Histomorphometric analysis for boneparameters showed highly significant difference in overall contrasted groups of implant in 2nd and 6th week interval.Conclusion: Dip coating method is an alternative coating technique for dental implant to enhance better boneimplant contact and improve osseointegration