The effects of different concentrations of Alum solutions on Mutans streptococci (in vitro study)

Abstract

Background: Alum has been used as a treatment medication in cases of oral and gingival ulcers, and also asantiseptic mouthwash. This study aimed to examine the effects of different concentrations of Alum on inhibition zone,viability counts and adherence ability of Mutans streptococci compared with deionized water and chlorhexidinegluconate in vitro.Materials and methods: The study dealt with an in vitro study to establish a concentration of Alum mouthrinse thatwould have the minimum inhibitory concentration and minimum bacteriocidal concentration. The second partevaluated the anti-adherence ability of the experimental agents.Results: This study found that the antibacterial effect of Alum increases with its concentration from 50 to 10000 PPMbut still weaker than 0.1% chlorhexidine gluconate. Only concentrations of 5000 and 10000 PPM showed negativeadherence of Mutans streptococci to the tooth surface.Conclusions: This study found that the antibacterial effect of Alum increases with its concentration from 50 to 10000PPM but still weaker than 0.1% chlorhexidine gluconate. Only concentrations of 5000 and 10000 PPM showednegative adherence of Mutans streptococci to the tooth surface