Hypocholesterolemic effect of Cymbopogon citratus in Rabbits.

Abstract

The current study was designed to examine the effect of an aqueous extract of Cymbopogon citratus leaves on the level of total serum cholesterol for normal and hypercholesterolemic rabbits. The results showed that the treatment of rabbits with an aqueous extract of Cymbopogon citratus leaves in concentration of 100 mg / ml and therapeutic dose of 5 ml/ kg / day via oral administration and for ten days , reduced significantly (P ‹ 0.05) the total serum cholesterol ( TC) level in induced hypercholesterolemic rabbits ( group D ) from (501.67±28.81) mg/100ml to ( 441.59±29.78 ) mg/100ml ,While no significant reduction was observed in the level of total serum cholesterol for treated healthy( normal ) rabbits ( group B ) were about from ( 127. 33 ± 9.44 ) mg/100ml befor treated to(130.09±0.23 ) mg/100ml after treated with the aqueous extract for ten days.