Prevalence of HBV among Hemodialysis patients in Mosul city, Iraq

Abstract

Hemodialysis patients [HD] seem to be at considerable risk of infection, therefore the aim of this study was carried out to determine the seroprevalence of Hepatitis B Virus among hemodialysis patients living in the Mosul city of Iraq.This study includes (70) patients , (43) Male and (27) Female, the age group ranged between less than 10 years to 60 years, and the mean age was 37.1 years, which was considerable percentage of HBV in patients above 50 years (7.1%), while the average percentage of HBV less than 50 age(2.24%). This study included age, gender, quantitative of blood pints transfusion, and episodes of big time spent on [HD] hemodialysis .This study showed that male [HD] patients had higher HBV prevalence than females (14.2%, 4.2%) respectively.Hemodialysis patients are at high risk for viral hepatitis infections due to the higher number of blood transfusion sessions range about less 5 pints to more 20 pints, in our study the prevalence of HBV was increased significantly with increasing the number of blood units transfused . Duration long term dialysis was less 2 year and more than 10 years in 4.2% of HBV positive patients, ( 2-4 ) years and ( 8-10 ) years in 1.4% of cases, and (4-6) years and (6-8) years in 2.8% of them, the mean time of dialysis ( 5.4 ) years. As well as it was used Enzyme Linked Immuno-Sorbent Assay (ELISA) technique to detect HBsAg and confirm the positive results by used Polymerase Chain Reaction (PCR) to detect HBV-DNA.The result was showed (13) positive with HBV in hemodialysis patients by ELISA technique, but (12) positive with HBV-DNA by used PCR .