Synthesis of Some New  4-{2-[chloro(4-substituted methyl]-2-methylhydrazino}-7-nitro-2,1,3-benzoxadiazole  Derivatives and  Study their Biological Activity

Olfa A.Naif

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Synthesis of Some New 4-{2-[chloro(4-substituted methyl]-2-methylhydrazino}-7-nitro-2,1,3-benzoxadiazole Derivatives and Study their Biological Activity

Olfa A.Naif

Al-Mustansiriyah Journal of Science
2010, Volume 21, Issue 3, Pages 51-64

Abstract

In this work aseries, 4-{2-[chloro(4-substituted)methyl]-2-methylhydrazino}-7-nitro-2,1,3-benzoxadiazole (8-12) were prepared from the reaction of the corresponding Schiff bases (2-7) with benzoyl chloride , which upon refluxing with thiourea in absolute ethanol in the presence of Na2CO3 for 5hrs yielded the corresponding thiourease compound.(13-15). The synthesized compounds have been characterized by using some spectral data (FT-IR and UV) nd.C.H.N The biological activity for their benzoxadiazole derivatives were studied against tow species of bacterial Eschericha coil and Staphylococcus aureus.

Year	Total	Jan	Feb	Mar	Apr	May	Jun	Jul	Aug	Sep	Oct	Nov	Dec
2023	2	2
2022	33	4	3	2	5	4	2	3	3	4	1	1	1
2021	34	3	4			4	12	3	3	1			4
2020	18		3	1	3	2	5	2					2
2019	13						2	3	1		2	3	2
2018	4					1	2				1
2017	13		1		1	3			3		1		4
2016	24	1	2	5	2		3		7	2	1		1
2015	13		1	3	1	1		3			1	1	2

Synthesis of Some New 4-{2-[chloro(4-substituted methyl]-2-methylhydrazino}-7-nitro-2,1,3-benzoxadiazole Derivatives and Study their Biological Activity

Abstract

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