@Article{, title={A Salivary Calcium Binding Protein in Patients with Oral Squamous Cell Carcinoma in Relation to Smoking}, author={Wisam Hamid Edan وسام حميد عيدان and Sulafa Khalid El-Samarrai سلافة خالد السامرائي}, journal={Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد}, volume={28}, number={2}, pages={149-151}, year={2016}, abstract={Background: Calcium binding protein regulates many important cellular functions such as cell proliferation, cellmotility and differentiation. Over-expression of calcium BP was detected in different human cancers, includingoral squamous cell carcinoma (OSCC). Therefore the aim of the present study was to evaluate the role ofcalcium binding protein in OSCC, quantified in stimulated saliva, and its association with smoking.Materials and methods: The present study included 20 patients with oral squamous cell carcinoma who used tobe smokers, and 40 control subjects. Calcium binding protein was assessed by ELISA technique, in stimulatedsaliva collected from all groups.Results: Salivary calcium binding protein was significantly higher in smoker patients with oral squamous cellcarcinoma than smoker and non- smoker control healthy looking subjects.Conclusions: Salivary calcium binding protein play a significant role, as a non-invasive approach, in the earlydiagnosis and follow up of oral squamous cell carcinoma patients

} }