@Article{, title={A Comparative Immunohistochemical Expression of Cyclin D1 in Keratocystic Odontogenic Tumor, Dentigerous and Radicular Cysts}, author={Yasamin Hamid Al-Amiri ياسمين حامد and Lehadh M. Al-Azzawi لحاظ العزواي}, journal={Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد}, volume={28}, number={1}, pages={92-98}, year={2016}, abstract={Background: Odontogenic cysts include a group of osseodestructive lesions that frequently affect the jaws. Thosecysts could derive from odontogenic epithelium and occur in the tooth-bearing regions of the jaws. The aims of thisstudy were to evaluate the immunohistochemical expression of Cyclin D1 in Keratocystic Odontogenic Tumor,Dentigerous cyst and Radicular cyst in epithelium and connective tissue capsule.Materials and Methods: In this study, thirty formalin fixed paraffin embedded tissue blocks of Odontogenic cysts andTumor, consist of 14 Keratocystic Odontogenic Tumor, 8 dentigerous cysts and 8 radicular cysts were analyzedimmunohistochemically for the presence of Cyclin D1 proteins.Results: Strong to moderate expression of Cyclin D1 in epithelium was found in Keratocystic Odontogenic Tumorcases with positive cases percentage was (85.7%). Statistical significant differences (P<0.001) observed whencomparing the three lesions. Immunoreactivity of Cyclin D1 in stroma of Keratocystic Odontogenic Tumor was higherthan in dentigerous cysts and radicular cysts cases. However, the difference was not statistically significant (P<0.067).Conclusion: The results of this study propose that high expression rate of Cyclin D1 might be one of the reasons foraggressive behavior of Keratocystic Odontogenic Tumor and high recurrence rate

} }