TY - JOUR ID - TI - Evaluating the effect of silver nanoparticles incorporation on antifungal activity and some properties of soft denture lining material AU - Moamin I. Issa مؤمن ابراهيم عيسى AU - Nabeel Abdul-Fattah نبيل عبد الفتاح PY - 2015 VL - 27 IS - 2 SP - 17 EP - 23 JO - Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد SN - 18171869 23115270 AB - Background: Colonization of soft denture liners by Candida albicans and other microorganisms continued to be aserious problem. The aim of this study was to evaluate the effect of incorporating silver nanoparticles into heat curedacrylic-based soft denture liner on the antifungal activity, and on water sorption, solubility, shear bond strength andcolor change of the soft lining material. Furthermore, evaluating the amount of silver released.Materials and methods: Silver nanoparticles were incorporated into soft denture liner in different percentages (0.05%,0.1% and 0.2% by weight). Four hundred and twenty specimens were prepared and divided into five groupsaccording to the test to be performed. The antifungal activity of the soft liner/AgNPs composite was evaluated inthree different periods by using (viable count of C. albicans and disk-diffusion test). The amount of silver released inartificial saliva was measured by atomic absorption spectroscopy. The water sorptions, solubility, shear bond strengthand color change was measured and the results were statistically analyzed.Results:All experimental groups showed a highly significant decrease in colony forming units of C. albicans incomparison to control group. There was no inhibition zone around any test specimen of any test group. There was nosilver detected to be released. The addition of AgNPs resulted in a highly significant decrease in water sorption, whileonly 0.2% group showed highly significant decrease in solubility. Non significant differences in shear bond strengthwere found. A highly significant increase in light absorption percentage was observed in all experimental groups.Conclusion: The addition of AgNPs helps to produce soft denture liner with antifungal properties. Silver was notdetected to be released. This addition resulted in decrease in water sorption, and did not affect the shear bondstrength and it increased the opacity of the material

ER -