TY - JOUR ID - TI - The Effect of Platelet-Rich Plasma on Osseointegration Period of Dental Implants AU - Mahammed W. Al-Gailani AU - Thair Abdul-Lateef ثائر عبد اللطيف PY - 2015 VL - 27 IS - 4 SP - 101 EP - 106 JO - Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد SN - 18171869 23115270 AB - Background: The preparation of Platelet-rich plasma (PRP) is minimally invasive way, simple, low cost to obtainnatural autologous growth factors and is now being widely used in different fields of medicine for its ability toincrease the regeneration potential of tissue. The aim of this study was to investigate the effect of local application ofautologous PRP gel on acceleration rate of osseointegration period by clinical assessment accomplished bydetermining the changes in implant stability during 3 months healing period using resonance frequency analysis(RFA).Materials and methods: A total of 28 dental implants were inserted in edentulous maxillae or mandibles of 13 patientsusing a split mouth design, i.e. each patient was received at least two dental implants at the same session, oneimplant was implanted in association with PRP which was placed locally in one site, to serve as PRP group, and theother implant was placed without PRP, to serve as a control group. Both groups were followed with repeated implantstability measurement by means of resonance frequency analysis at different time intervals (at the time of implantplacement, 8th week, and 12th week postoperatively).Results: There was no obvious statistically significant difference in mean ISQ between PRP and control groups (P >0.05) at baseline, 8 weeks, and 12 weeks postoperatively.Conclusions: Within the limitations of the present study, no appreciable clinical effect was observed to acceleratethe rate of osseointegration of sandblasted acid-etched endosseous dental implants when using topical applicationof autologous PRP gel into the prepared drill holes

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