@Article{, title={Clinical Evaluation of Infantile Spasm on a Sample of Children, Baghdad –Iraq}, author={Adel A. Kareem and Hula R. Shreef and Husham Zuhair Hammoodi}, journal={Karbala Journal of Medicine مجلة كربلاء الطبية}, volume={12}, number={1}, pages={4094-4102}, year={2019}, abstract={background: Infantile spasms (IS) are a seizure disorder that was first described by William West in 1841 and has been referred to as West syndrome. It is a disorder that affects mostly those in the first year of life. Infantile spasms in most cases associated with psychomotor delay and specific pattern of electroencephalogram (EEG) pattern called hypsarrhythmia. “West syndrome” is often generally used to describe this triad.Objective: to study clinical profile, EEG and treatment response for infantile spasm.Patient and method: Fifty six patients with infantile spasm have been enrolled in the study who seeks medical advice from August 2015 to December 2017, conducted at the Children's Neurological Ward and Outpatient Clinics of Welfare teaching hospital, Medical City Complex, Baghdad. with onset of spasm between 1-12 month age and shows significant finding when EEG done for they and consequently at least 2 years period follow up.Result; A total of 56 consecutive cases of infantile spasms with significant finding in their EEG were recorded; male to female ratio is 57%:43%. Structural defect in the brain was the predominant cause, 16% of children, the reason had not been proven. The Outcome was only favorable in 5 (11%) of children. Many variables like age of onset, sex, lagtimeand co-morbidity were not significant and did not affect final outcome.Conclusion; The current study highlights the clinical Evaluation of children with infantile spasm, in term of delayed diagnosis, etiology of structural brain defect, and favorable response to steroids.

} }