TY - JOUR ID - TI - Pulse Pressure Index as a Discriminator of Predicting the Cardiovascular Events in Hypertensive Patients Treated with Drugs Acting on Angiotensinogen-Angiotensin Pathway AU - Yagub S. Saleh AU - Ismail I. Hussein AU - Marwan S. Al-Nimer PY - 2019 VL - 15 IS - 1 SP - 1 EP - 5 JO - Al- Anbar Medical Journal مجلة الأنبار الطبية SN - 27066207 26643154 AB - Background: Pulse pressure index as a function of pulse pressure divided by systolic bloodpressure served a useful predictor of cardiovascular events.Objectives: Our aim was to assess the pulse pressure index as a discriminating variable ofpredicting cardiovascular events in untreated hypertensive patients and treated with one memberof angiotensin converting enzyme inhibitors or angiotensin receptor blockers by using the scores ofFramingham study.Materials and methods: This observational cross-sectional study, including 140 patients whogrouped into; Group I (n = 30): untreated hypertensive patients; Group II (n = 60): patientstreated with angiotensin receptor blockers; and Group III (n = 50): patients treated withangiotensin converting enzyme inhibitors. Anthropometric measurements, lipid profile, and bloodpressure were determined. The probability of ten-year of cardiovascular events was calculatedaccording to the Framingham study scores using The University of Edinburgh Cardiovascular RiskCalculator (http://cvrisk.mvm.ed.ac.uk/calculator/calc.asp).Results: There is a non-significant difference between Groups and within Groups of age, smokinghabit, and the values of the cardio metabolic risk factors. Pulse pressure index as an independentrisk factor found to be a significant discriminator of 10-year prediction of cardiovascular events byusing the receiving operating characteristic curves.Conclusion: The pulse pressure index is a useful discriminator of predicting cardiovascular events,and it will improve the Framingham prediction risk among hypertensive patients

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