TY - JOUR
ID -
TI - Salivary and plasma analysis of oxidative stress biomarkers in end stage renal failure patients
AU - Raja H. Al-jubouri
AU - Bahaa A. A. Al- Rahman Hadi
PY - 2011
VL - 23
IS - 2
SP - 46
EP - 50
JO - Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد
SN - 18171869 23115270
AB -
ABSTRACT
Background: End Stage renal disease represents a clinical state or condition in which there has been an irreversible
loss of endogenous renal function. To evaluate role of oxidative stress & anti oxidant in chronic renal failure patients
by measuring malondialdehyde & uric acid in their plasma and saliva in comparison with apparently healthy control
group.
Materials &methods: The study was conducted on 60 Chronic renal failure patients at Al-Hussein teaching hospital,
Karbala (Iraq) & 30 apparently healthy control group. Laboratory measurements of salivary &plasma levels of
oxidants ,antioxidants markers (MDA, uric acid) was done on hemodialysis patients compared to age & sex matched
apparently healthy control group.
Results: Salivary & plasma (malondialdehyde , uric acid ) showed highly significant differences between chronic
renal failure patients & apparently healthy control groups. This study was the first study that measure salivary MDA in
end stage renal failure patients.
Conclusion: Higher salivary, plasma oxidants & antioxidants concentrations of end stage renal failure patients with
increase salivary components disturbances in comparison with apparently healthy control group.
Key wards: Hemodialysis, Malondialdehyde, Uric acid. (J Bagh Coll Dentistry 2011;23(46-50).
ER -