TY - JOUR ID - TI - Clinical Evaluation of Seizures in Pediatric Intensive Care Unit in Babylon Teaching Hospital - A Retrospective Study AU - Wijdan Abed Sabti PY - 2020 VL - 13 IS - 2 SP - 2390 EP - 2396 JO - Karbala Journal of Medicine مجلة كربلاء الطبية SN - 19905483 29580889 AB - Background: A seizure is a paroxysmal time limited change in motor activity and /or behavior that results from abnormal electrical activity in the brain and most common seizures in children are provoked by somatic disorders or originating outside the brain.The aim of our study was to retrospectively evaluate all the patients with seizure re-quired admission to Pediatric Intensive Care Unit to determine the etiologies of sei-zure and their clinical outcome.Materials and Methods: A total of 378 children were admitted to PICU from Janu-ary 2019 to January 2020, 40 patients were eligible, Age ranged above one month to 16 years. Seizures were organized as epileptic or acute symptomatic, pediatric risk fac-tors, classification of diagnosis, description and duration of convulsion, medications given to the patients with duration of admission to Intensive Care Unit and immediate outcome.Results: The numbers of males equal to the females, mean age was 14.6 months, the most common causes of seizures were acute symptomatic, most frequent coexistent diagnosis was infectious diseases and 70% progress to status epilepticus.Seizures were generalized in (28) 70% patients, (12) 30% had focal. Intravenous phenytoin and phenobarbiton was second line of therapy in 57.5%.Acute symptomatic seizures were usually new onset, and duration was shorter. Epilep-tic seizures tended to be recurrent and were likely to progress to SE.However type of seizures didn’t change severity of the disease, also laboratory test results, requirement for mechanical ventilation, duration of admission and mortality were not significant between epileptic/ acute symptomatic patients.Conclusion: Seizure in critically ill children, which may evolve in to status epilepticus is an important condition that require attention regardless of cause. Intensified educa-tional programs for Pediatric Intensive Care Unit physicians and international guide-lines are necessary for a more efficient approach to children with seizures.

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