TY - JOUR ID - TI - Classification of non‑Hodgkin lymphoma in the Middle Euphrates Region of Iraq according to the World Health Organization classification AU - Dr. Ahmed Mjali PY - 2021 VL - 10 IS - 2 SP - 170 EP - 175 JO - Iraq Joural of Hematology المجلة العراقية لامراض الدم SN - 20728069 25432702 AB - BACKGROUND: Non‑Hodgkin lymphoma (NHL) patterns vary worldwide in relation to demographicand environmental factors.AIM: The objective of our study was to identify subtypes of NHL in the Middle Euphrates Region ofIraq according to the World Health Organization (WHO) modified classification.MATERIALS AND METHODS: A retrospective descriptive study was carried out at Al‑Hussein CancerCenter in Karbala, Iraq, on 385 patients diagnosed with NHL between January 2012 and August2020. Patient ages ranged between 1 and 96 years. They included 204 males and 181 females. Allpatients were diagnosed by tissue biopsy, confirmed by immunohistochemistry markers, and classifiedaccording to WHO classification. Any patient with inconclusive results was excluded from the study.RESULTS: Among total NHL patients, males were (53%) and females were (47%) with a male: femaleratio of (1.12:1). B‑cell lymphoma was diagnosed in (92.47%) and T cell lymphoma in (7.53%).Diffuse large B‑cell Lymphoma (DLBCL) was the most frequent B‑cell subtype (54.02%) followedby Burkitt’s lymphoma (BL) (14.02%), while peripheral T‑cell lymphoma was the most commonT‑cell subtype (2.08%). About (61.82%) of patients were nodal, and (38.18%) were extranodal. Theintestine was the most frequent extranodal site (34.69%).CONCLUSION: Among our patients, there were high frequencies of DLBCL, extra nodal primaries andintestinal BL. Follicular lymphoma and small lymphocytic lymphoma were uncommon in our region.These results were similar to the Middle Eastern NHL patterns but differed from the western patterns.

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