TY - JOUR ID - TI - Assessment of Sympathetic Activity of Adrenal Medullae in Patients with Kidney Stone Treated by Extracorporeal Shock Wave Lithotripsy (ESWL) AU - Rusul Abdul Kadhim Mohammed AU - Samir Sawadi Hammoud AU - Wadhah A. Almarzooq PY - 2022 VL - 19 IS - 4 SP - 697 EP - 702 JO - Medical Journal of Babylon مجلة بابل الطبية SN - 1812156X 23126760 AB - Background: Extracorporeal shock wave lithotripsy (ESWL) is the most widely used method for treating kidney and upper uretericstones smaller than 2 cm due to its effectiveness, safety, non-invasive, and an outpatient procedure. Objective: The present study aimsto assess the effect of ESWL on the sympathetic activity of adrenal medullae in patients with renal stone. Materials and Methods: Across-sectional study was conducted at the ESWL Unit, AL-Hilla Teaching Hospital, Babil Province, Iraq on 50 patients from October1, 2021 to April 30, 2022. Before and right after an ESWL session, patients underwent a history, physical examination and laboratorytests to measure their levels of serum catecholamines (CAs). Results: The results of this study revealed that there is a significantincrease of serum epinephrine and norepinephrine levels (P-value <0.001) after ESWL session. There is a significant (P <0.1) increasein epinephrine and norepinephrine levels in patients treated for upper pole renal stones when compared with mid and lower polerenal stones after having an ESWL session. Changing the lithotripter’s parameters (energy, frequency, and number of shock waves)did not significantly (P > 0.05) correlate with the level of both norepinephrine and epinephrine in the serum after the ESWL session.Conclusion: The study found that patients with renal stones treated with ESWL had elevated serum CA levels after the session. The CAlevel correlates with the site of stone (the stone comes near to the adrenal medullae as there was an increase in the CA level), whereasit was unaffected by the lithotripter’s parameters.

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