TY - JOUR ID - TI - Salivary antioxidants and physicochemical characteristics related to periodontal disease among a group of old adults AU - Baydaa A. Yas AU - Ban S. Diab PY - 2009 VL - 21 IS - 3 SP - 103 EP - 107 JO - Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد SN - 18171869 23115270 AB - Background: Old adults experienced pronounced oral changes. Saliva composition particularly the antioxidantsshowed significant changes with advancing age. The aims of this study were to assess salivary antioxidants and lipidperoxidation biomarker (malondialdehyde) levels in addition to salivary physicochemical characteristics and theireffect on periodontal disease among a group of old adults in comparison with middle-aged.Materials and methods: The study group consisted of all old adults (35 subjects) aged 55-65 years in comparison withall middle-aged (35 subjects) aged 30-40 years at the Textile factory in Mosul city who fitted the criteria of the study.Periodontal disease was evaluated by using the gingival index, periodontal pocket depth and clinical attachmentlevel. Unstimulated salivary samples were collected and salivary flow rate and pH were determined. Salivary samplesthen were chemically analyzed for the detection of salivary antioxidants (total protein, albumin, vitamin E, vitamin Cand uric acid) and lipid peroxidation biomarker (malondialdehyde) in addition to salivary constituents as urea,calcium, phosphorous and magnesium.Results: Antioxidants level (total protein, albumin, vitamin E, and vitamin C) was lower among old adults comparedto middle-aged ones with significant difference for vitamin C only. Malondialdehyde was slightly higher among oldadults with no significant difference. Statistically no significant difference could be found regarding salivary flow rateand pH between the two age groups. Salivary constituents (urea, calcium, phosphorous and magnesium) showedno significant difference between the two age groups. Mean gingival index was highly significantly higher amongold adults. The extent of pocket depth was higher among old adults at ≥4 and ≥5 mm thresholds but ≥7 mm thresholdwas absent among them. Clinical attachment level extent was higher among old adults at all thresholds of severity.Salivary albumin revealed inverse significant correlation with severe thresholds of clinical attachment level (i.e. ≥7, ≥8,≥9 mm). Lipid peroxidation (malondialdehyde) showed positive highly significant correlation with ≥9 mm attachmentlevel threshold among old adults. Salivary flow rate revealed inverse correlation with almost all clinical attachmentlevel thresholds among old adults.Conclusions: Periodontal disease revealed higher severity among old adults. Salivary antioxidants andphysicochemical characteristics were found to affect periodontal health status among old adults

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