@Article{, title={Paget’s Disease of Bone}, author={Abd Alsahib, M.*}, journal={Karbala Journal of Medicine مجلة كربلاء الطبية}, volume={1 no.3}, number={2}, pages={197-202}, year={2007}, abstract={background: Paget’s disease of bone is a focal disorder of bone metabolism that results inenlargement of the affected bone and deformity, a process that is sometimes accompanied by painand/or disfigurement (1). The disease is common in Western Europe, USA, and Australia but very rare inMiddle East and Arabian Peninsula. Here we reported seven un-relative patients with Paget’s disease inKarbala between 1995-2005. Their ages ranged between 51-75 years. One patient was polyostotic and theremaining were monostotic types. Four cases presented with fracture femur, the 5th patient withundisplaced fracture tibia and the last two cases with pain in tibial bones and knee joints. Radiologicalcriteria of Paget’s disease were more obvious in cases of tibial involvement than femoral cases in whichhistopathological examination confirmed the diagnosis. Serum alkaline phosphatas at time of presentationranged between 20-34 KAU/100ml, the higher level was in polyostotic case. The purpose of this paper isto shed light on this rare entity and the variety of presentations.

} }