@Article{, title={VCAM-1 Expression in Endometerium with Human}, author={*Asmaa B Al-Obaidi MBChB,MSc **Manal Adnan Habib MBChB,PhD *Shatha Al-ZuhairyMBChB,FICOG}, journal={Al-Kindy College Medical Journal مجلة كلية الطب الكندي}, volume={8}, number={1}, pages={14-17}, year={2012}, abstract={Background: To elucidate the possible role of human cytomegalovirus in pregnancy loss through induction of certain pro-inflammatory adhesion molecules.Methods: Paraffin embedded sections of curate samples were obtained from 34 women had spontaneous abortion, and 5 women had elective termination of pregnancy (as control), and then subjected for immunohistochemistry analysis to detect human cytomegalovirus (HCMV) early protein and VCAM-1 molecule.Results: Nine out of 34 women with spontaneous abortion were positive for HCMV early protein, with asignificantly higher expression of VCAM-1 in HCMV positive cases as compared with HCMV negative and the control groups (p = 0.05, 0.001 respectively).Conclusion: HCMV infection may play an important role in the pathology of pregnancy loss on multidirectional bases include inducing the surface expression of pro-inflammatory adhesion molecules like VCAM-1.Key wards: human cytomegalovirus, VCAM-1, Abortion

} }