TY - JOUR ID - TI - Dental caries and salivary lipid soluble vitamins among group of women aged 30-39 years with breast cancer AU - Basma A.Kanan بسمة كنعان AU - Ban S. Diab بان ذياب PY - 2012 VL - 24 IS - 1 SP - 85 EP - 89 JO - Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد SN - 18171869 23115270 AB - Background: Breast cancer is one of the serious diseases affect women in large percentage that may cause generalsystemic changes, these systemic changes affect on saliva composition especially lipid soluble vitamins (A ,D ,E ,K)which lead to an adverse effect on oral health status. This study were conducted to evaluate the concentration oflipid soluble vitamins (A, D, E, K) in saliva and their relation to dental caries among breast cancer and compared tocontrol group.Materials and Methods: The total sample composed of 60 females aged 30_39 years attending Al_Yarmook TeachingHospital, 30 females newly diagnosed with breast cancer at stages II and III before taking any treatment and surgeryand 30 female without clinical signs of breast cancer (control group).The diagnosis and recording of dental carieswas through the application of DMFS index according to criteria of Manji et al (1989). Salivary sample were collectedunder standardized condition, stimulated salivary samples were collected according to(Tenovuo and Lagerlöf, 1994)and saliva analyzed for estimation of lipid soluble vitamins (A ,D ,E ,K) by using high performance liquidchromatography (HPLC) apparatus.Results: The percentage of dental caries occurrence was 100% among breast cancer group and control group. Ariesexperience (DMFS) was higher among breast cancer group (45.10±17.06) compared with control group (33.63±11.10)with no significant differences. Lipid soluble vitamins (A ,D ,E ,K ) were lower in breast cancer group compared tocontrol group with highly significant differences. Salivary lipid soluble vitamins A and E showed a not significantcorrelation in negative direction with dental caries experience (DMFS), while salivary lipid soluble vitamins D and Kshowed a not significant correlation in positive direction.Conclusions: Dental caries revealed higher percentage of occurrence among breast cancer group

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