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Background: Spirometry is important test performed in patients expect to have air way obstruction, assessment of intense reaction to inhalers (the trial of reversibility of air way blockade) is a normally utilized technique in clinical and academic studies. The consequences of this test are utilized to take choices on treatment, consideration, exclusion from diagnosis and other research thinks about, and for analytic marking [asthma versus chronic obstructive air way disease (COPD)]. Usually, the (FEV1) or (FVC) standards before and after giving of the bronchodilator are compared and the adjustment is processed to distinguish variations from the norm in lung volumes and air flow.Objective: The aim of this study was to investigate the effectiveness of FVC and PEFR as further constraints to evaluate bronchodilator reaction in asthmatic peoples with severe or moderate airflow blockade.Patients and methods: This study is cross sectional studyperformed in Baghdad teaching hospital where one hundred patient were enrolled in this study patients were detected with asthma and confirm airway blockade according to (GINA) guidelines.The pulmonary function for all members were investigated with a convenient spirometer (spiro-lab3 Spirometer) as stated by those measures from claiming American thoracic particular social order,The mean and standard deviation results of predicted% values pulmonary function test were also used for comparisons were measured by t-test. A p-value of ≤ 0.05 considered to be significant statistically.Results: The post bronchodilator (post –BD) results of FVC, PEFR are greater than pre- bronchodilator where are statistically significant P value = 0.00. the amount of the changes of FVC post (BD) was more than 400ml from pre (BD) and the amount of the changes of PEFR post (BD) more than 1000ml from the pre (BD) both were p value = 0.00.Conclusion: The asthmatic patients with moderate and severe airway obstruction, we observed that FVC and PEFR is a valuable important limit to FEV1 to evaluate reversibility reaction

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Abstarct

Background: Breast involvement by immunolymphoproliferative disorders is rare. Primary & secondary malignant lymphomas of the breast are much more common than multiple myeloma, of which only 18 cases were reported in previous literature, till the year 2000.Case presentation: We report a young female patient presented simultaneously with bilateral multiple breast masses & pathological fracture in right humorous that proved later on via histopathological examination to be a case of multiple myeloma associated with extramedullary plasmocytoma involving breasts.Discussion and Conclusion: There were diagnostic difficulties caused by the lack of specific radiological & sonographic features that differentiate between primary or secondary breast tumor & breast infiltration by immunolymphoproliferative disorders.Key words: Plasma cell diseases, plasmocytoma, multiple myeloma, breast mass

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