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Immunological study of patients with asthma
Alaa J.H. and Thanaa A.M
Journal of University of Babylon, 2013, Volume 21, Issue 7, Pages 2400-2407
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An immunological study were performed to estimation the concentrations of immunoglobulin IgE
,
IL-4
,
IL-13 and PGE2 by ELISA
,
calculate the total and differential WBCs counts of patients with asthma
,
as well as the relationship between this disease and gender in Babylon province . The study reveals that the IgE and IL – 4 levels were significantly increased
,
p<0.05 in patients
,
second and third age categories compared with healthy subject . The results illustrated that the patients show a significant elevation in IL – 13 levels in first
,
p<0.01
,
second
,
p<0.05 and third
,
p<0.01 age categories respectively compared with control group
,
furthermore
,
the study revealed that the concentration of prostaglandin –E2
,
PGE2 show highly significant elevation
,
p<0.05 in patients compared with healthy individuals . The results displays that there is no significant differences
,
p<0.05 in total WBCs count between patients and control group
,
and the same results was in means of neutrophils
,
lymphocytes and monocytes
,
while there were significantly increased
,
p<0.05 in eosinophils
,
first and second groups and basophils
,
all groups in patients compared with healthy subject
,
furthermore
,
the results reveals increased ratio of disease in females compared with males .
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