Preventive and Therapeutic Activities For Some Food Exposure to Radiation

Abstract

The current study was designed to find out preventive and therapeutic effect of the grapefruit juice Citrus paradise and watercress Eruca sativa and whey protein against harmful effects of exposure to the gamma dose (5 RIM X-ray , 76 KV dose).Seventy five animals 2-3 mon , 750-950 g were randomized in to 15 groups of 5 rabbits each and were treated as below (1) no treatment (control) (2) exposed to radiation Kama Ɣ-ray only group, (3) X-ray only, (4) grape fruit juice + X-ray, (5) X-ray + grapefruit juice, (6) Watercress group + X-ray, (7) X-ray + watercress, (8) whey protein + X-ray, (9) X-ray + whey protein, (10) Grapefruit juice + Ɣ-ray, (11) Ɣ-ray + grapefruit juice, (12) watercress + Ɣ-ray, (13) Ɣ-ray + watercress, (14) whey protein + Ɣ -ray, ( 15) Ɣ -ray + whey protein. The results showed significant increase (P≤0.05) in the creatinine Malondialdehyde, Peroxi nitrite level Alanine-amino Trans frase ALT Aspartat- Aspartate-amino Trans frase AST activities.And significant reduction in the Glutathione (GSH) level also abnormal histological changes in liver after radiation with Ɣ-ray and X-ray exposure.Administration of citrus paradisi juice , Eruca sativa leaves and whey protein powder before or post Ɣ –ray and X-ray exposure gave asignificant decrease in the creatinine malondialdehyde , peroxinitrite level , ALT AST activites and asignificant in creas in (GSH) level with a high improvement in liver. so this study improved the importance of this foods in radiation therapy.