دراسة مقاومة بكتريا Klebsiella pnumoniae للمضادات الحياتية باستخدام جهازVitek2 المعزولة من عينات سريرية

Abstract

This study was carried out to investigate the role of the bacterium Klebsiella pnumoniae as a pathogenic bacterium in the urinary tract infections and diarrhea in humans as well as other bacterial etiology. The study included screening for this bacteria in clinical samples from patients suffering from urinary tract infection and diarrhea ,for both gender and different ages and outpatients to the Hashemiya General Hospital.The current study aims to determine the antibiotics sensitivity of the bacterial isolates isolated from clinical samples against of different classes of antibiotics using Vitek2 technique. A total of 222 samples were collected from patients with urinary tract infections and diarrhea 42 samples were found to Klebsiella pnumoniae and 120 samples were found due to other samples bacterial pathogens and other 18 samples were negative for bacterial culture. The isolates of the bacteria Klebsiella pneumoniae was detected against to a number of antibiotics using Vitek2 system. The results of sensitivity to antibiotics showed That most of isolates were resistant to Ticarcillin 42(100%), Piperacillin 42(100%), Ceftazidime30(71.4%), Cefepime30(71.4%), Aztreonam 30 (71.4%) and TrimethoprimeSulfament 24 (57.2%). The study also showed that the most effective antibiotics against isolates were Tobramycin42(100%), Ciprofloxacin 42 (100%),Amikacin 42 (100%),Imipenem 36(85.7%), Meropenem 36 (85.7%), PiperacillinTazobactam 30(71.4%) ,Gentamycin 30 (71.4%), and Minocycline 30 (71.4%) ,Therefore it is considered to be typical treatment to Klebsiella pnumoniae infections.