Epidemiological study of Cytomegalovirus (CMV) ,Toxoplasma gondii(T.g) and Rubella virus among aborted women in Misan province, Iraq

Abstract

AbstractThe aim of this study was to determine the seroprevalence of these infections and more effect in aborted women in different period of gestation. Prenatal screening for antibodies to Toxoplasma gondii (T.g) rubella virus and cytomegalovirus (CMV) infectious agents provided good information about effective treatment which decrease abortions women.The data obtained from the records at Al -sader hospital in misan province.The total number of sera collected and tested for serum samples was 1143 samples. antibodies to Toxoplasma gondii ( T.g) rubella virus and cytomegalovirus (CMV) IgM and IgG which were caused serious congenital infections of Pregnant women were assayed by ELISA method using Abbott kits (Axsym, Abbott, USA) according to the manufacturer’s instructions. From all 1143 pregnants women, seropositivity for anti-toxoplasma IgG+IgM antibodies together was found in 389 (34.03%) while The seropositivities for anti-CMV IgG+IgM together was found in901 (78.82%) Whilst The seropositivities for anti-rubella IgG+IgM together were found in 626 (54.76 %). from among 1143 of samples which recorded in hospital about 97 (8.48%) of women had abortion with infections . Whilst the number of abortion women without any infections of these diseases was 12 (1.04%) women .the age of aborted women which was most abortion was limited in (21 to 30). Out of the total number of women tested the number of women who had previous abortion in their disease history was 150.the number of women who live in rural area with previous miscarriage 150 women while the number 0f women who live in urban area was 44.the IgG titer was significantly higher in seropositive cases with aborted women than seropositive controls (5.18 ± 1.99 vs. 2.00 ± 0.81, P < 0.001).