Epidemiological and Biochemical changes of patients infected with Blastocystis hominis and Irritable bowel syndrome

Abstract

This study was design to examined fecal samples of patients with irritable bowel syndrome (IBS) to detect a relationship between Blastocystis hominis infection and IBS. This study was began at January till December 2015 in Kindi teaching hospital / Baghdad .380 patients with IBS and 55 apparently healthy people as control group after making sure of their medical history, clinical and laboratory examinations were done of all subjects which included direct smears examination of stool and culturing of parasite . Infection of B. hominis occurred in males at high rate at October (5.8%) and lowest rate during January (3.7%). Where as in females high rate infection was at August (5.8%) and lowest rate during January (2.1%) Blastocystis hominis infection rate in males represent nearly equal in villages and cities (31%,32% respectively) while in females the infection was higher in villages(21%) than in cities (16%).Incidence of Blastocystis hominis infection was the highest ( 11.0%) at age group 10-15 year. This study also detect that 65.3% of infections were diagnosed by direct smear preparation and 34.7% were diagnosed by culturing.There was a significant differences of total bilirubin levels in the IBS patient group compared to control group (p<0.001).This study represented no significant differences of urea and creatinine levels among patients when compared to control group (p ˂ 0.05).