Effect of casein phosphopeptides stabilize amorphous calcium phosphate on hardness of enamel

Abstract

ABSTRACT
Background: Casein phosphopeptides(Cpp) stabilize amorphous calcium phosphate (Acp) localized in dental
plaque and are anticarcinogenic in animals and insitu human caries model, CPP have ability to stabilize calcium
phosphate in dental plaque.
Materials and methods: Ten extracted human teeth were buccolingually cut into two halves and embedded in resin
providing 20 specimens with buccal and lingual experimental sites (treated with lemon juice for demineralization). All
specimens were rinsed with deionized water and the hardness measurements were reported Tthe demineralized
specimens were randomly divided in 4 groups with 4 regimes use Cpp-Acp ( group 1) artificial saliva (group 2), Cpp-
Acp and artificial saliva ( group 3) and deionized water as control.
Results: Higher hardness value for group I in comparism to all study groups. ( P≤0.05).
Conclusion: Cpp-Acp can increase the hardness of enamel eroded by lemon juice. The remineralization effect of
Cpp-Acp is significantly higher than that of artificial saliva in vitro.
Key words: Tooth erosion, casein phosphopeptide-amorphous calcium phosphate, hardness. (J Bagh Coll Dentistry
2010;22(3):62-64).