Some Biochemical Parameters And Histological Changes caused by sun set Yellow overload in Neuzland male rabbits.

Abstract

Ten male rabbits were divided into two groups (5/group) , the first group was intubated with tap water and served as control group . Rabbits in the second group were intubated orally with 0.05 mg /kg B.W daily for 12 weeks . Fasting blood samples were collected after each 4 weeks of experiment for measuring some libratory tests in serum of bloods rabbits . The result of this study showed a significant (P<0.05) increase in Total cholesterol (TC) , Triacylglycerol (TAG) , Low density lipoprotein –cholesterol (LDL-C) and Very Low density lipoprotein –cholesterol (VLDL-C) and AST , ALT activities with significant (P<0.05) decrease in High density lipoprotein (HDL-C) and also histological examination showed inflammatory infiltration in the liver section .