THE PHYTOCHEMICAL COMPOSITION AND THE EFFECT OF METHANOLIC EXTRACT OF TYPHA DOMINGENSIS PERS. FRUITE ON SOME BIOCHEMICAL PARAMETERS IN ADULT MALE RABBITS

Abstract

This study was undertaken to find the phytochemical composition of Typha domingensis pers. Fruite and the effect of the methanolic extract on some biochemical parameters such as serum glucose , cholesterol , total protein , AST, ALT, and ALP enzymes in adult male rabbits after oral administration of different doses ( 500,1000,1500 mg/ Kg) daily for 30 days . Rabbits were divided into four groups 6 rabbits in each , group I animals received only 3 ml normal saline orally as control ,while groups(II ,III and IV) were orally administrated (500,1000,1500 mg/kg) of methanolic extract respectively .The result of the present study indicated that Typha domingensis pers. Fruite contains alkaloids, phenols, flavonoids, tannins and saponins,. Significantly decreased (p< 0.05) was observed in serum level of glucose, AST, ALT and ALP while, no significant different (p>0.05) in serum level of cholesterol and total proteins were observed as compared with control group. This study concluded that methanolic extract of Typha domingensis pers. Fruite can act as anti-diabetic and hepatoprotective agent .INTRODUCTIONThe Typha