Study of the Antimicrobial effect of Melia azedarach L. plant

Abstract

This study was aimed to evaluate the antimicrobial activity of the leaf extracts of Melia azedarach L. plant against different pathogenic microorganisms such as (Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, klebsilla sp., Candida albicans). Two plant extracts (Aqueous and ethanolic) under four different concentrations (25, 50, 75, 100) mg/ml were used by Agar-well diffusion method. Chemical detection of extract showed that the extracts contain tannins, flavonoids, terpins, steriods, alkaloids, and saponins. Aqueous leaf extract showed no effect against all tested microorganisms at (25, 50, 75, 100) mg/ml concentration except Candida albicans which was sensitive to 100mg/ml concentration. While Ethanolic (80%) leaf extract showed sensitivity on Staphylococcus aureus at 100mg/ml concentration.