Isolation and identification of oral candida spp. from leukemic children under chemotherapy and treatment with extraction of different plants in vitro

Abstract

Background: Oral candidiasis represents a serious problem for children with cancer during chemotherapy. The aim ofthis study was isolation and identification of oral candida spp.Materials and method: Sixty five oral swabs were taken from children suffering from leukemia.Results and Conclusion: The results of isolation in this research showed prevalence of candida.albicans at 64.62 %and C.glabrata 20%. In vitro antifungal activity of aqueous of (Quercus infectoria , Cinnamon , punica Granatum) atconcentration 100-500mg/ml against ( C. albicans, C.glabrata, C.tropicalis and C .famata ) showed the Quercusinfectoria was more active against ( C. albicans, C.glabrata, C.tropicalis and C .famata ) compared with othersplants extracts which used in this study.