Estimation of Concentration Leptin hormone in Blood Serum of suffering breast cancer women

Abstract

The aim of this study is to estimate the concentration of Leptin hormone and glutathione , Malondialdehyde and cholesterol, triglycerides in blood serum of breast cancer women. This work is performed in Tikrit teaching Hospital by collecting 40 samples of breast cancer women(25 non smoking patients and 15 smoking) and 15 samples of control group. The results showed increase in Leptin hormone in P<0.05 of breast cancer women compared with breast cancer smoking women there was a significant decrease in the concentration leptin hormone. The results showed increase in Malondialdehyde level and decrease in glutathione level of blood serum in breast cancer . Also results showed a significant decrease in glutathione level and significant increase in malondialdehyde level in females smokers with cancer . There was a significant increase (P<0.05) concentration of cholesterol and triglycerides level in blood serum of breast cancer women compared to control group .