Determination of IGE level in Asthmatic Adult Males Patients on Attack and Rest Period

Abstract

Abstract Sixty male patients with asthma were included in this study, their age ranged between 18-24 years (mean 20 ±1.3). Forty-five were in attack state and fifteen were in rest (between the attacks). All cases were admitted to Al-Rasheed military hospital during November 2001 and April 2002.Twenty age matched apparently healthy en were included as a negative control. Eight males with signs and symptoms of asthma (mostly chronic bronchitis patients) were regarded as a positive control. Ten ml of blood sample were withdrawn from each patient as well as from controls.IgE level was measured by enzyme linked immunosorbant assay (ELISA) in which a significant elevation were noticed in both groups attack and rest groups in comparison with control groups.Key wards: IGE, Asthmatic, immune response.