تحضير مركبات اروماتية جديدة متعددة المجاميع الهيدروكسيلية للبنزين وبعض مشتقاته Synthesis Of New Poly Hydroxy Aromatic Compounds For Benzene And Some Its Derivatives

Abstract

In this research involved the preparation of many aromatic compounds Contained poly hydroxyl groups for Benzene derivatives ,the compounds may have biological activity and large application in drugs , fuels , fragrances , To achieve this objective , glycerol triformate was synthesized first by treatment of glycerol [1] with 3 moles of formic acid by using Catalyst Poly vinyl benzene sulphonic acid ,The hydroxyl group at C-1 , C-2 and C-3 were converted in to glycerol triformate ester, the resulting ester Glycerol triformate was reacted with aromatic compounds which include ( Benzene, Toluene , Chloro benzene , Bromo benzene , P-xylene) in presence of Aluminum Silicate as a catalyst. After the preparation of the compounds, they were hydrolyzed in the presence of hydrochloric acid as a catalyst to give the following new compounds were obtained:- 1. 2-Phenyl propane-1,2,3- triol. (A7 ) 2. 2,2´-(p- phenylene)- propane-1,2,3-triol.(A8) 3. 2-(4-Chloro phenyl)-propane-1,2,3-triol.(A9) 2-(4-Bromo phenyl)-propane-1,2,3-triol.(A10) 4.5. 2-(2,5-Dimethyl phenyl)-propane-1,2,3-triol.(A11)All compounds studied and characterized by H1 NMR , IR and C.H.N, the ratio of the product is estimated for all the preparation compounds , and boiling point is also measured