Study of Pathological Changes of Sheep liver associated with Parasitic infestation

Abstract

Histopathological changes of (50) liver samples of sheep infected with hydatid cyst and liver flucks. Selected from butcher shops in Mosul province, have been investigated. In regard to hydatid cyst infected samples, Lesions showed variation between atrophy and necrosis of hepatocytes accompanied with lymphocytes infiltration cutting that cyst. Other samples showed fatty change of hepatocytes concomitant with congestion of central veins few sections revealed liquifactive necrosis infiltrated with inflammatory cells while others showed sever fibrosis of hepatic tissue. In most liver sections infected with liver flucks lesions characterized by cholangitis accompanied with biliary hyperplasia. Some samples showed fatty, necrosis of hepatocytes and central vein congestion, few samples revealed focal lymphocytes infiltration concomitant with prevalent visceral emboli sever fibrosis with hepatic hemorrhage was seen in two samples only. In conclusion, this study clarify the most pathogenic lesions of sheep liver infected with hydatid cyst and liver flucks in Mosul area.